ABSTRACT
Objective To explore the feasibility and application value of sonography in the evaluation of oropharynx in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods The oropharynx of forty-four patients with OSAHS and forty-four healthy subjects selected as the control group were separately examined by ultrasonography.The parameters including anterior-posterior diameter and the lateral diameter of oropharyngeal airway of the end-deep inspiratory and end-deep expiratory,thickness and wide of tongue base,lingual wide,lingual height,distance from mandibular plane to hyoid bone and distance from tongue base to mandibular plane were obtained for statistical analysis and compared between the two groups.Correlation analysis of above parameters plane with body mass index (BMI) were carried out. Results The anatomy of the oropharynx was well shown on sonography.When compared with the control group,the lateral diameter of oropharyngeal airway,thickness of tongue base,lingual height,lingual wide and distance from mandibular plane to hyoid bone also showed significant statistically differences between the OSAHS patients group and the control group (all P <0.01).The wide of tongue base,thickness of tongue base,lingual wide,lingual height,distance from mandibular plane to hyoid bone,and distance from tongue base to mandibular plane in OSAHS patients group were positively correlated with BMI( r =0.533,0.415, 0.555,0.349,0.378,0.419;all P <0.05).The wide of tongue base and lateral diameter of oropharyngeal airway in the control group were negatively correlated with BMI ( r = -0.324,-0.405,-0.317;all P <0.05).Conclusions Ultrasonography can be used to assist in the assessment of OSAHS,which can provide an important reference for clinical diagnosis and therapeutic effect evaluation of OSAHS.
ABSTRACT
Objective To explore ultrasonic image for the normal anatomy of the larynx,and provide the basis of ultrasonic diagnosis in laryngeal diseases.Methods Ultrasound anatomy for the larynx was established by way of comparing the structures of four corpses and ultrasonic imaging of the larynx of normal control group.Results Ultrasonic image for the normal anatomy of the larynx was established by comparing the anatomy tomography of corpses and ultrasonic imaging of the larynx of normal control group.Conclusions Ultrasonography could be applied in the examination of the laryngeal diseases as it could show unambiguous ultrasonic imagings of the larynx,and adding an important complementary technique to clinical medicine.
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effects of the method of soothing the liver and regulating qi on expression of gastrin and somatostatin in hypothalamus and gastric antrum of functional dyspepsia model rats.</p><p><b>METHOD</b>The 32 rats were randomly divided into normal group, model group, Chaihu Shugansan group and domperidone group (n = 8). The functional dyspepsia model was established by constantly squeezing their tails and mean while saline, Chaihu Shugansan decoction and domperidone suspension were administered respectively to 4 groups by gavage. The expression of gastrin and somatostatin in hypothalamus and gastric antrum of rats by immunohistochemical were detected 3 weeks later.</p><p><b>RESULT</b>The expression of GAS in the hypothalamus and gastric antrum of model group were less than those of normal group (P < 0.05, P < 0.01), while the expression of SS in the hypothalamus and gastric antrum in Model group were significantly increased than those of normal group (P < 0.01). The expression of GAS and SS in gastric antrum of Chaihu Shugansan group and domperidone group were increased and decreased respectively, and the differences were significant (P < 0.05, P < 0.01). There were no obvious difference about expression of GAS, SS in the hypothalamus between domperidone group and model group. GAS expression in hypothalamus of Chaihu Shugansan group were increased than those of normal group but there was no obvious difference in SS expression in hypothalamus between Chaihu Shugansan group and model group.</p><p><b>CONCLUSION</b>The method of soothing the liver and regulating qi can increase GAS expression in central and peripheral and decrease SS expression in peripheral gastric antrum, which may be one of its therapeutic mechanisms on functional dyspepsia.</p>